Lila Solnica-Krezel Lab

Publications


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Papers

Chen J, Castelvecchi, GD, Li-Villarreal N, Raught B, Krezel AM, McNeill H, Solnica-Krezel L. Developmental Cell. 2018 May 7;45(3):376-391. Atypical Cadherin Dachsous1b interacts with Ttc28 and Aurora B to control microtubule dynamics in embryonic cleavages.

Williams ML, Sawada A, Budine T, Yin C, Gontarz P, Solnica-Krezel L. Nature Communications. 2018 9:1319.Gon4l promotes embryonic axis extension by regulating notochord cell polarity and boundary formation through repression of cell adhesion genes.

Chen J, Xia L, Bruchas ML, Solnica-Krezel L. Developmental Biology. 2017 Oct 15;430(2):385-396.Imaging early embryonic calcium activity with GCaMP6s transgenic zebrafish.

Liu Y, Sepich DS, Solnica-Krezel L. (2017) Stat3/Cdc25a-dependent cell proliferation promotes embryonic axis extension during zebrafish gastrulation. PLoS Genetics 13(2):e1006564

Kaiko GE, Ryu SH, Koues OI, Collins PL, Solnica-Krezel L, Pearce EJ, Pearce EL, Oltz EM, Stappenbeck TS.  (2016)  The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites. Cell 16;165(7):1708-20.

Sepich, D.S. and Solnica-Krezel, L. (2016) Intracellular Golgi complex organization reveals tissue specific polarity during zebrafish embryogenesis. Developmental Dynamics. 245, 678-91.

Nishioka, T., Arima, N., Kano, K., Hama, K., Itai, E., Yukiura, H., Kise, R., Inoue, A., Kim, S.H., Solnica-Krezel, L., Moolenaar, W., Chun, J., and Aoki, J. (2016) ATX-LPA1 axis contributes to proliferation of chondrocytes by regulating fibronectin assembly leading to proper cartilage formation. Scientific Reports. 6, 23433.

Li C, Ma H, Wang Y, Cao Z, Graves-Deal R, et al. Excess PLAC8 promotes an unconventional ERK2-dependent EMT in colon cancer. J Clin Invest. 2014 May;124(5):2172-87. PubMed PMID: 24691442; PubMed Central PMCID: PMC4001536 Li-Villarreal, N., Forbes, M.M., Loza, A.J., Chen, J., Ma, T., Helde, K., Moens, C.B., Shin, J., Sawada, A., Hindes, A.E., Dubrulle, J., Schier, A.F., Longmore, G.D., Marlow, F.L., Solnica-Krezel, L. (2015) Dachsous1b cadherin regulates actin and microtubule cytoskeleton during early zebrafish embryogenesis. Development. 142, 2704-18. – Correction published (2016) in Development. 143, 1832.

Li C, Ma H, Wang Y, Cao Z, Graves-Deal R, et al. Excess PLAC8 promotes an unconventional ERK2-dependent EMT in colon cancer. J Clin Invest. 2014 May;124(5):2172-87. PubMed PMID: 24691442; PubMed Central PMCID: PMC4001536 Roszko, I., Sepich D. S., Jessen, J.R., Chandrasekhar A, Solnica-Krezel L. (2015) A dynamic intracellular distribution of Vangl2 accompanies cell polarization during zebrafish gastrulation. Development. 142, 2508-2520.

Li C, Ma H, Wang Y, Cao Z, Graves-Deal R, et al. Excess PLAC8 promotes an unconventional ERK2-dependent EMT in colon cancer. J Clin Invest. 2014 May;124(5):2172-87. PubMed PMID: 24691442; PubMed Central PMCID: PMC4001536 Li C, Ma H, Wang Y, Cao Z, Graves-Deal R, et al. Excess PLAC8 promotes an unconventional ERK2-dependent EMT in colon cancer. J Clin Invest. 2014 May;124(5):2172-87. PubMed PMID: 24691442; PubMed Central PMCID: PMC4001536.

Shin J, Chen J, Solnica-Krezel L. Efficient homologous recombination-mediated genome engineering in zebrafish using TALE nucleases. Development. 2014 Oct;141(19):3807-18. PubMed PMID: 25249466; PubMed Central PMCID: PMC4197590 Shin J, Chen J, Solnica-Krezel L. Efficient homologous recombination-mediated genome engineering in zebrafish using TALE nucleases. Development. 2014 Oct;141(19):3807-18. PubMed PMID: 25249466; PubMed Central PMCID: PMC4197590.

Li X, Roszko, I, Sepich, DS, Hamm, H, Marlow, FL, Solnica-Krezel, L. The adhesion GPCR Gpr125 modulates Dishevelled distribution and planar cell polarity signaling. Development. 2013.140, 3028-3039. PubMed PMID: 23821037; PubMed Central PMCID: PMC3699285 Li X, Roszko, I, Sepich, DS, Hamm, H, Marlow, FL, Solnica-Krezel, L. The adhesion GPCR Gpr125 modulates Dishevelled distribution and planar cell polarity signaling. Development. 2013.140, 3028-3039. PubMed PMID:  23821037; PubMed Central PMCID:  PMC3699285.

Wu SY, Shin J, Sepich DS, Solnica-Krezel L. Chemokine GPCR signaling inhibits ?-catenin during zebrafish axis formation. PLoS Biol. 2012;10(10):e1001403. PubMed PMID: 23055828; PubMed Central PMCID: PMC3467228 Wu SY, Shin J, Sepich DS, Solnica-Krezel L. Chemokine GPCR signaling inhibits β-catenin during zebrafish axis formation. PLoS Biol. 2012;10(10):e1001403. PubMed PMID: 23055828; PubMed Central PMCID: PMC3467228.

pdf_icon Kim SH, Speirs CK, Solnica-Krezel L, Ess KC. Zebrafish model of tuberous sclerosis complex reveals cell-autonomous and non-cell-autonomous functions of mutant tuberin. Dis Model Mech. 2011 Mar;4(2):255-67. PubMed PMID: 20959633; PubMed Central PMCID: PMC3046101.

pdf_icon Speirs CK, Jernigan KK, Kim SH, Cha YI, Lin F, et al. Prostaglandin Gbetagamma signaling stimulates gastrulation movements by limiting cell adhesion through Snai1a stabilization. Development. 2010 Apr;137(8):1327-37. PubMed PMID: 20332150; PubMed Central PMCID: PMC2847468.

pdf_icon Lin F, Chen S, Sepich DS, Panizzi JR, Clendenon SG, et al. Galpha12/13 regulate epiboly by inhibiting β-cadherin activity and modulating the actin cytoskeleton. J Cell Biol. 2009 Mar 23;184(6):909-21. PubMed PMID: 19307601; PubMed Central PMCID: PMC2664974.

pdf_icon Geng X, Speirs C, Lagutin O, Inbal A, Liu W, et al. Haploinsufficiency of Six3 fails to activate Sonic hedgehog expression in the ventral forebrain and causes holoprosencephaly. Dev Cell. 2008 Aug;15(2):236-47. PubMed PMID: 18694563; PubMed Central PMCID: PMC2597207.

Yin C, Kiskowski M, Pouille PA, Farge E, Solnica-Krezel L. Cooperation of polarized cell intercalations drives convergence and extension of presomitic mesoderm during zebrafish gastrulation. J Cell Biol. 2008 Jan 14;180(1):221-32. PubMed PMID: 18195109; PubMed Central PMCID: PMC2213609 Yin C, Kiskowski M, Pouille PA, Farge E, Solnica-Krezel L. Cooperation of polarized cell intercalations drives convergence and extension of presomitic mesoderm during zebrafish gastrulation. J Cell Biol. 2008 Jan 14;180(1):221-32. PubMed PMID: 18195109; PubMed Central PMCID: PMC2213609.

pdf_icon Zeng XX, Wilm TP, Sepich DS, Solnica-Krezel L. Apelin and its receptor control heart field formation during zebrafish gastrulation. Dev Cell. 2007 Mar;12(3):391-402. PubMed PMID: 17336905.

pdf_icon Mendelsohn BA, Yin C, Johnson SL, Wilm TP, Solnica-Krezel L, et al. Atp7a determines a hierarchy of copper metabolism essential for notochord development. Cell Metab. 2006 Aug;4(2):155-62. PubMed PMID: 16890543.

pdf_icon Jessen JR, Topczewski J, Bingham S, Sepich DS, Marlow F, et al. Zebrafish trilobite identifies new roles for Strabismus in gastrulation and neuronal movements. Nat Cell Biol. 2002 Aug;4(8):610-5. PubMed PMID: 12105418; PubMed Central PMCID: PMC2219916.

pdf_icon Topczewski J, Sepich DS, Myers DC, Walker C, Amores A, et al. The zebrafish glypican knypek controls cell polarity during gastrulation movements of convergent extension. Dev Cell. 2001 Aug;1(2):251-64. PubMed PMID: 11702784.

pdf_icon Gonzalez EM, Fekany-Lee K, Carmany-Rampey A, Erter C, Topczewski J, et al. Head and trunk in zebrafish arise via coinhibition of BMP signaling by bozozok and chordino. Genes Dev. 2000 Dec 15;14(24):3087-92. PubMed PMID: 11124801; PubMed Central PMCID: PMC317122.

pdf_icon Fekany K, Yamanaka Y, Leung T, Sirotkin HI, Topczewski J, et al. The zebrafish bozozok locus encodes Dharma, a homeodomain protein essential for induction of gastrula organizer and dorsoanterior embryonic structures. Development. 1999 Apr;126(7):1427-38. PubMed PMID: 10068636.

pdf_icon Driever W, Solnica-Krezel L, Schier AF, Neuhauss SC, Malicki J, et al. A genetic screen for mutations affecting embryogenesis in zebrafish. Development. 1996 Dec;123:37-46. PubMed PMID: 9007227.

pdf_icon Solnica-Krezel L, Stemple DL, Mountcastle-Shah E, Rangini Z, Neuhauss SC, et al. Mutations affecting cell fates and cellular rearrangements during gastrulation in zebrafish. Development. 1996 Dec;123:67-80. PubMed PMID: 9007230.

pdf_icon Solnica-Krezel L, Schier AF, Driever W. Efficient recovery of ENU-induced mutations from the zebrafish germline. Genetics. 1994 Apr;136(4):1401-20. PubMed PMID: 8013916; PubMed Central PMCID: PMC1205920.