 |  |  | ||
| Welcome to Matt Atehortua, Research Technician I Matt Atehortua joined the Solnica-Krezel lab in June 2023 as a Research Tech I. | Take your Lab to the Ball Game with the CRM The Solnica-Krezel lab joined in the Center of Regenerative Medicine “Take your lab to the ball game” day to watch the St. Louis Cardinals on May 4, 2023. | Missouri History Museum Lunch The Solnica-Krezel lab enjoyed lunch at Cafe St. Louis in the Missouri History Museum on March 23, 2023. | ||
|
|
|
| ||
Congratulations!Lilianna Solnica-Krezel, PhD, was awarded the Edwin G. Conklin Medal in Developmental Biology. Established in 1995, the Edwin G. Conklin Medal in Developmental Biology is awarded annually by the Society for Developmental Biology (SDB) to recognize a developmental biologist who has made and is continuing to make extraordinary research contributions to the field and is an excellent mentor who has helped train the next generation of outstanding scientists. | Lilianna Solnica-Krezel, PhD, and Jimann Shin, PhD, received a two-year R21 grant award from the NIH, Office of the Director, beginning February 15, 2023, for her project entitled, “Increasing the efficiency and range of prime editing for disease modeling in zebrafish.” | Lilianna Solnica-Krezel, PhD, Aaron Johnson, PhD, Kristen Kroll, PhD, David Ornitz, MD, PhD, and Stephen Pak, PhD, have received a five-year R01 grant award from the NIH/Eunice Kennedy Shriver National Institute of Child Health & Human Development beginning December 20, 2022, for their project entitled, “Multi-organism platform for functional assessment of human birth defect associated genomic variants.” | ||
 |  |
| ||
| Lilianna Solnica-Krezel, PhD, received a five-year competitive renewal from the National Institute of Health’s Eunice Kennedy Shriver National Institute of Child Health & Human Development, beginning June 15, 2022, for her project entitled “Forward and reverse genetic studies of AIS and spine development in zebrafish.” This project is part of a program project grant with Dr. Carol Wise through UT Southwestern. |
Welcome to Sarah Stamp, Postbaccalaureate ResearcherSarah Stamp joined the Solnica-Krezel lab in August 2022 as a postbaccalaureate researcher. |
New PublicationCARMIL3 is important for cell migration and morphogenesis during early development in zebrafish. Stark BC, Gao Y, Sepich DS, Belk L, Culver MA, Hu B, Mekel M, Ferris W, Shin J, Solnica-Krezel L, Lin F, Cooper JA. Dev Biol. 2022 Jan;481:148-159. | ||
|
|
|
| ||
New PublicationThe zebrafish issue: 25 years on. Mullins MC, Navajas Acedo J, Priya R, Solnica-Krezel L, Wilson SW. Development. 2021 Dec 15;148(24). | Dr. Lilianna Solnica-Krezel (PI) and Luis Batista, Ph.D. (Co-I), have received a one-year grant award from the Undiagnosed Disease Network for their project entitled “Using zebrafish as an animal model and human pluripotent stem cells to evaluate pathogenicity and define disease mechanisms for an ENY2 variant found in UDN544529”. | Lila Solnica-Krezel, Alan A. and Edith L. Wolff Distinguished Professor of Developmental Biology and Head, received the 2021 Carl and Gerty Cori Faculty Achievement Award. | ||
|
|
|
| ||
New Publication20 years of Developmental Cell: Looking back. Chory J, Olson EN, Solnica-Krezel L, Munro S, Fuchs E, St Johnston D, Lefebvre V, Coupland G, Millar Se, Lin H. Dev Cell. 2021 Dec 6;56(23):3181-3184. | Dr. Lilianna Solnica-Krezel has received a competitive renewal for a five-year Maximizing Investigators’ Research Award from the National Institute of General Medical Sciences starting May 1, 2021, for her project entitled, “Inductive and morphogenetic processes shaping the zebrafish embryonic axes. “ |
New PublicationMYH3-associated distal arthrogryposis zebrafish model is normalized with para-aminoblebbistatin. Whittle J, Antunes L, Harris M, Upshaw Z, Sepich DS, Johnson AN, Mokalled M, Solnica-Krezel L, Dobbs MB, Gurnett CA. EMBO Mol Med. 2020 Nov 6;12(11):e12356. | ||
|  |  | ||
| Lila Solnica-Krezel, Ph.D., John Cooper, M.D., Ph.D., and Fang Lin, Ph.D. (University of Iowa), have received a one-year grant award from the Undiagnosed Diseases Network for their project titled, “Using zebrafish as an animal model to evaluate pathogenicity and define disease mechanisms for a CARMIL3 variant (p.Gln928Glu) found in UDN552818”. |
Congratulations to Wyndham Ferris!Wyndham Ferris, a Research Technician in the Solnica-Krezel lab, will be starting graduate school in the fall in the Washington University Division of Biology and Biomedical Sciences Developmental, Regenerative and Stem Cell Biology Program. |
Welcome to Alvin Randall, Postbaccalaureate ResearcherAlvin Randall joined the Solnica-Krezel lab in June 2021 as a postbaccalaureate researcher. Alvin joined the inaugural group of postbaccalaureate researchers as part of a program established by the Department of Developmental Biology and the Center of Regenerative Medicine. | ||
|  |  | ||
| Dr. Lilianna Solnica-Krezel has received a competitive renewal for a five-year Maximizing Investigators’ Research Award from the National Institute of General Medical Sciences starting May 1, 2021, for her project entitled, “Inductive and morphogenetic processes shaping the zebrafish embryonic axes. “ |
Welcome to Jacob Brush, Research Technician IIJacob joined the Solnica-Krezel lab in February 2021. In the lab he is working on a genetic screen for maternal-effect mutations affecting early zebrafish embryogenesis. |
Welcome to Blerta Stringa, Ph.D., PostdocDr. Blerta Stringa joined the Solnica-Krezel lab in October as a postdoctoral fellow. Dr. Stringa’s research will involve the interrogation of the function of zebrafish genes that we have recently identified by mapping several maternal effect mutant loci associated with developmental arrests at early gastrulation and segmentation stages. | ||
 |  |  | ||
New PublicationPostembryonic screen for mutations affecting spine development in zebrafish. Gray RS, Gonzalez R, Ackerman S, Minowa R, Griest J, Bayrak M, Troutwine B, Canter S, Monk K, Sepich D, and Solnica-Krezel L. Dev biol. 2020 Dec 5;471:18-33. |
Congratulations to Dr. Kyaw Thu Minn!Dr. Kyaw Thu Minn defended his thesis in fine style in October and will be starting in a consulting role at Charles River Associates. Congratulations, Minn! |
New PublicationMinn KT, Fu YC, He S, Dietmann S, George S, Anastasio M, Morris, SA, and Solnica-Krezel L. Elife. 2020 Nov. 9:e59445. | ||
 |  |  | ||
Congratulations to the newly minted Dr. Castelvecchi!Dr. Gina Castelvecchi defended her thesis on July 27, 2020, and will be starting a technology transfer fellowship through the Walter Reed Army Institute of Research with the Department of Defense in Washington DC. Congrats, Gina! |
New PublicationNodal and planar cell polarity signaling cooperate to regulate zebrafish convergence and extension gastrulation movements. Williams, MLK and Solnica-Krezel L. Elife.2020 Apr 22;9:e54445. |
Congratulations to Lila Solnica-Krezel!Lila has been elected to the International Zebrafish Society Board of Directors as President-Elect. | ||
 |  |  | ||
New PublicationBudine, T., deSena-Tomas, C., Williams, MLK., Sepich, D., Targoff, K., Solnica-Krezel, L. Dev Biol. 2020 Jun 15;462(2):223-234. doi: 10.1016/j.ydbio.2020.03.002. Epub 2020 Apr 6. |
Margot Williams receives Chi-Bin Chien Award!Margot Williams, Ph.D., Assistant Professor in the Center for Precision Environmental Health and Department of Molecular and Cellular Biology at the Baylor College of Medicine, received the IZFS 2020 Chi-Bin Chien Award. Her outstanding research contributions and dedication to the zebrafish field truly characterize the spirit of Chi-Bin Chien. Congratulations! |
Gastrulation: From Embryonic Pattern To Form, edited by Lila Solnica-KrezelLila edited the recently published (January 20, 2020) Gastrulation: From Embryonic Pattern to Form, Volume 136, 1st edition. The work is a collection from leaders in the field of embryology development. | ||
 |  |  | ||
Welcome to Linwei Li, Ph.D., PostdocDr. Linwei Li joined the Solnica-Krezel lab in November 2019 as a postdoctoral fellow. Linwei’s research will be involving the genetic regulation of early embryogenesis in zebrafish, in particular the mechanisms that coordinate cell movements and fate specification during gastrulation. |
Congratulations to Isa Roszko!Isa Roszko (center), Scientist in the Lila Solnica-Krezel laboratory received FEBS Letters First Level Poster Prize at the 14th International Zebrafish Conference in Suzhou, China. Congratulations Isa! |
Congratulations to Lila Solnica-Krezel!Lila received the Nusslein-Volhard Award at the 2019 International Zebrafish Society meeting. The Nusslein-Volhard Award is from the European Society for Fish Models in Biology and Medicine (EuFishBioMed). | ||
 |  | | ||
Congratulations to Margot Williams!Margot Williams, Ph.D., Staff Scientist in the Solnica-Krezel lab has accepted a tenure-track position as an assistant professor in the Center for Precision Environmental Health and Department of Molecular and Cellular Biology at Baylor College of Medicine where she will start in the fall of 2019. |
Congratulations to Jiakun Chen!Jiakun was recently awarded the 2018 Irving Boime Publication Award for his publication entitled “Atypical Cadherin Dachsous1b interacts with Ttc28 and Aurora B to Control Microtuble Dynamics in Embryonic Cleavages”. The award was presented at the Department of Developmental Biology Holiday party, where Lila accepted the award on his behalf. Pictured left to right: Irving Boime, Lila Solnica-Krezel and Martin Matzuk. |
Congratulations to Lila Solnica-Krezel!The American Association for the Advancement of Science has bestowed upon her the lifetime honor of being an elected Fellow in recognition of her distinguished contributions to the field of developmental biology, particularly advancing forward genetics to define genetic mechanisms underlying inductive and morphogenetic processes during vertebrate embryogenesis. | ||
 |  |  | ||
Congratulations to Margot L. K. Williams!Margot Williams, Ph.D., Staff Scientist in the Solnica-Krezel lab received a two-year K99 Career Award from the National Institutes of Health , National Institute of Child Health & Human Development beginning September 1, 2018, for her project entitled “Defining Direct and Indirect Roles of Nodal Signaling in Convergence & Extension”. |
Terin BudineOur recent graduate student alumna, Terin Budine, joined the Office of Technology Management at Washington University in St. Louis. | Atypical Cadherin Dachsous1b interact with Ttc28 and Aurora B to control microtubule dynamics in embryonic cleavages. ChenJ, Castelvecchi GD, Li-Villarreal N, Raught B, Krezel AM, McNeill H, Solnica-Krezel L. Developmental Cell. 2018 May 7;45(3):376-391 | ||
|
|
|  | ||
| Gon4l promotes embryonic axis extension by regulating notochord cell polarity and boundary formation through repression of cell adhesion genes. Williams ML, Sawada A, Budine T, Yin C, Gontarz P, Solnica-Krezel L. Nature Communications. 2018 9:1319. | Imaging early embryonic calcium activity with GCaMP6s transgenic zebrafish. Chen J, Xia L, Bruchas ML, Solnica-Krezel L. Developmental Biology. 2017 Oct 15;430(2):385-396. |
Jiakun ChenOur recent graduate student alumnus, Jiakun Chen, joined the labs of Dr. Kelly Monk and Dr. Marc Freeman as a postdoctoral fellow at the Vollum Institute. | ||
 |  |  | ||
| Stat3/Cdc25a-dependent cell proliferation promotes embryonic axis extension during zebrafish gastrulation. Liu Y, Sepich DS, Solnica-Krezel, L. PLoS Genetics. 2017 Feb 21; 13(2):e1006564. |
Gina CastelvecchiGina Castelvecchi was awarded the Rita Levi-Montalcini Award for Best Student Poster Presentation for her work entitled, “Dachsous regulates microtubules during zebrafish gastrulation,” at the 26th Annual Developmental, Regenerative and Stem Cell retreat. Congrats, Gina! | Dr. Lilianna Solnica-Krezel has received a five-year, Research Program Project grant, in collaboration with Dr. Carol Wise of the University of Texas Southwestern and Dr. Nadav Ahituv of the University of California-San Francisco, from the Eunice Kennedy Shriver National Institute of Child Health & Human Development starting September 1, 2016, for her project entitled, “Forward and Reverse Genetic Studies of AIS and Spine Development in Zebrafish.” This award is one of three projects in the multi-PI Program Project grant entitled, “Developmental Mechanisms of Human Idiopathic Scoliosis.” | ||
 |  | | ||
| Intracellular Golgi Complex organization reveals tissue specific polarity during zebrafish embryogenesis. Sepich, DS and Solnica-Krezel L. Developmental Dynamics. 2016 Jun;245(6):678-91. | The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites. Kaiko GE, Ryu SH, Koues OI, Collins PL, Solnica-Krezel L, Pearce EJ, Pearce EL, Oltz EM, Stappenbeck TS. Cell. 2016 Jun 16;165(7):1708-20. | Dr. Lilianna Solnica-Krezel has received a five-year Maximizing Investigators’ Research Award from the National Institute of General Medical Sciences starting May 1, 2016, for her project entitled, “Inductive and morphogenetic processes shaping the zebrafish embryonic axes. “ | ||
 |  |  | ||
Nanbing “Jade” LiOur recent graduate student alumna, Jade Li, joined Mary E. Dickenson’s Lab at Baylor College of Medicine as a Postdoctoral Fellow |
Yinzi LiuOur graduate student alumna, Yinzi Liu, joined Health Advances, LCC, consulting company. |
Ryan GrayOur former postdoctoral fellow, is establishing his independent laboratory to study scoliosis in zebrafish and mouse models in Department of Pediatrics, The University of Texas at Austin, Dell Medical School, in Austin, TX. | ||
 |  |  | ||
| Dachsous1b cadherin regulates actin and microtubule cytoskeleton during early zebrafish embryogenesis.
Li-Villarreal N, Forbes MM, Loza AJ, Chen J, Ma T, Helde K, Moens CB, Shin J, Sawada A, Hindes AE, Dubrulle J, Schier AF, Longmore GD, Marlow FL, Solnica-Krezel L. Development. 2015 Jul 9. | Efficient homologous recombination-mediated genome engineering in zebrafish using TALE nucleases.
Shin, J., Chen, J., Solnica-Krezel L. Development. 2014 Oct: 141 (19):3807-18. | ATX-LPA1 axis contributes to proliferation of chondrocytes by regulating fibronectin assembly leading to proper cartilage formation.
Nishioka T1, Arima N1, Kano K1, Hama K1, Itai E1, Yukiura H1, Kise R1, Inoue A1,2, Kim SH3, Solnica-Krezel L4, Moolenaar WH5, Chun J6, Aoki J1,7. Sci Rep. 2016 Mar 23;6:23433. | ||
 |  |  | ||
Fang LinOur former postdoctoral fellow has been promoted to Associate Professor with Tenure in the Department of Anatomy & Cell Biology at the University of Iowa Carver College of Medicine. |
Terry Van RaayOur former postdoctoral fellow has been promoted to Associate Professor with Tenure in the Department of Molecular & Cell Biology at the University Guelph in Canada. | A dynamic intracellular distribution of Vangl2 accompanies cell polarization during zebrafish gastrulation.
Roszko I, S Sepich D, Jessen JR, Chandrasekhar A, Solnica-Krezel L. Development. 2015 Jul 15;142(14):2508-20. doi: 10.1242/dev.119032. | ||
Menu
